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Meso Scale Diagnostics LLC
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Image Search Results
Journal: Molecular & Cellular Proteomics : MCP
Article Title: Uncovering the Depths of the Human Proteome: Antibody-based Technologies for Ultrasensitive Multiplexed Protein Detection and Quantification
doi: 10.1016/j.mcpro.2021.100155
Figure Lengend Snippet: Electrochemiluminescence (ECL) multiarray. Capture antibodies are printed onto 96- or 384-well microtiter plates at precise, predetermined positions. Each spot (1–10) is a barcode for a specific analyte of interest. Biological sample is incubated in the wells, allowing for binding of the target proteins. After washing, detection antibody that is conjugated to a ruthenium tag is added. After final wash steps, tripropylamine (TPA) is added before the electrode surfaces of the plate are stimulated, causing the ruthenium label to create an ECL signal in the form of light. Redrawn based on https://www.mesoscale.com/en/technical_resources/our_technology .
Article Snippet: The
Techniques: Electrochemiluminescence, Incubation, Binding Assay
Journal: Molecular & Cellular Proteomics : MCP
Article Title: Uncovering the Depths of the Human Proteome: Antibody-based Technologies for Ultrasensitive Multiplexed Protein Detection and Quantification
doi: 10.1016/j.mcpro.2021.100155
Figure Lengend Snippet: Technical parameters of commercial immunoassay-based multiplex proteomics platforms
Article Snippet: The
Techniques: Multiplex Assay, Intra Assay, Clinical Proteomics, Electrochemiluminescence, Cell Culture, Luminex, Modification
Journal: Molecular & Cellular Proteomics : MCP
Article Title: Uncovering the Depths of the Human Proteome: Antibody-based Technologies for Ultrasensitive Multiplexed Protein Detection and Quantification
doi: 10.1016/j.mcpro.2021.100155
Figure Lengend Snippet: Electrochemiluminescence (ECL) multiarray. Capture antibodies are printed onto 96- or 384-well microtiter plates at precise, predetermined positions. Each spot (1–10) is a barcode for a specific analyte of interest. Biological sample is incubated in the wells, allowing for binding of the target proteins. After washing, detection antibody that is conjugated to a ruthenium tag is added. After final wash steps, tripropylamine (TPA) is added before the electrode surfaces of the plate are stimulated, causing the ruthenium label to create an ECL signal in the form of light. Redrawn based on https://www.mesoscale.com/en/technical_resources/our_technology .
Article Snippet: Yeung et al. ( ) performed a cross-platform assessment of nine ultrasensitive technologies, including
Techniques: Electrochemiluminescence, Incubation, Binding Assay
Journal: Molecular & Cellular Proteomics : MCP
Article Title: Uncovering the Depths of the Human Proteome: Antibody-based Technologies for Ultrasensitive Multiplexed Protein Detection and Quantification
doi: 10.1016/j.mcpro.2021.100155
Figure Lengend Snippet: Technical parameters of commercial immunoassay-based multiplex proteomics platforms
Article Snippet: Yeung et al. ( ) performed a cross-platform assessment of nine ultrasensitive technologies, including
Techniques: Multiplex Assay, Intra Assay, Clinical Proteomics, Electrochemiluminescence, Cell Culture, Luminex, Modification